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Metabolomic Chemist

Department of Commerce
National Institute of Standards and Technology
Biochemical and Exposure Science Group

Summary

NIST is seeking a Metabolomic Chemist in Charleston, SC as a technical leader in high-order metrology. In this critical role, you will serve as a subject matter expert developing quantitative NMR (qNMR) techniques and advancing reference materials for metabolomics.

This notice is issued under direct-hire authority to recruit new talent to occupations for which NIST has a severe shortage of candidates.

Overview

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Accepting applications
Posted this week · Apply today
Due by 11:59 p.m. ET on June 15, 2026
Location
1 vacancy in the following location:
Work site options
Telework eligible
Yes—as determined by the agency policy.
Remote job
No
Relocation expenses reimbursed
No
Salary
$74,678 - $116,362 per year
Pay scale & grade
ZP 3
Promotion potential
3
Pay scale and grade determines the salary of the job.
Work schedule
Full-time
Travel Required
Not required
Appointment type
Permanent
Occupations and job series
Supervisory status
No
Federal service type
This job is in the Competitive Service
Represented by a union
No
Drug test
No
Security clearance
Not Required
Position sensitivity and risk
Non-sensitive (NS)/Low Risk
Jobs require a background check and some require a security clearance. The type depends on the job.
Background check type
Financial disclosure required
No
Some jobs require financial disclosure to identify conflicts of interests.
Announcement number
MML-646-26-12973344-DH
Control number
872191700

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Duties

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In this position, you will:

  • Implement sample preparation protocols and high-accuracy methods of analysis for biological molecules in calibration solutions, Standard Reference Materials (SRMs), biological matrix samples, Quality Assurance Program study materials and other reference materials.
  • Conduct certification measurements, stability evaluations and other material feasibility studies associated with NIST SRMs using NMR.
  • Conduct metabolomics experiments using NMR on reference materials and materials originating from outside collaborations.
  • Interpret metabolomic results from experiments using principles of biochemistry and analytical chemistry.
  • Prepare reports and manuscripts on experimental results.

Requirements

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Conditions of employment

  • U.S. citizenship
  • Males born after 12-31-59 must be registered for Selective Service
  • Suitable for Federal employment
  • Bargaining Unit Position: No

Qualifications

Basic Requirements:

A. Degree in physical sciences, life sciences, or engineering that includes 30 semester hours in chemistry, supplemented by course work in mathematics through differential and integral calculus, and at least 6 semester hours of physics.

OR

B. Combination of education and experience: Course work equivalent to a major as shown in A above, including at least 30 semester hours in chemistry, supplemented by mathematics through differential and integral calculus, and at least 6 semester hours of physics, plus appropriate experience or additional education.

IN ADDITION: To qualify, applicants must have at least one year (52 weeks) of specialized experience equivalent to the GS-9 grade level (ZP-II for NIST). Specialized experience is defined as experience in performing analytical characterization of biological materials, developing sample preparation techniques to assess identity and concentration of these materials, performing Nuclear Magnetic Resonance (NMR) analysis of biological and chemical samples, and maintaining accurate experimental records and summarizing data.

OR

Master's or equivalent graduate degree in related field.

OR

A combination of graduate education and specialized experience as defined in the additional requirements.

Experience refers to paid and unpaid experience, including volunteer work done through National Service programs (e.g., Peace Corps, AmeriCorps) and other organizations (e.g., professional; philanthropic; religious; spiritual; community, student, social). Volunteer work helps build critical competencies, knowledge, and skills and can provide valuable training and experience that translates directly to paid employment. You will receive credit for all qualifying experience, including volunteer experience.

The qualification requirements in this vacancy announcement are based on the U.S. Office of Personnel Management (OPM) Qualification Standards Handbook.

If requesting reconsideration of your qualification determination, please refer to the following site: Applicant Reconsideration

Education

This position has an education requirement. Transcripts must be submitted to validate that the education requirement has been met. Unofficial transcripts will be accepted in the application package. However, an official copy will be required before a final offer of employment.

Use of foreign education for qualifications. An accredited organization must evaluate education completed outside of the U.S. to ensure that it is comparable to education received in accredited institutions in the U.S. Click here to view a listing of accredited organizations from the Department of Education's website. A copy of the foreign education evaluation (containing the results with course-by-course listing) is required with your application.

Additional information

This position is covered under NIST's Alternative Personnel Management System (APMS), a pay-for-performance system with excellent HR flexibilities to help NIST recruit and retain top talent. Learn more about the APMS here!

  • We may share your application package with other selecting officials. Additional selections may be made through this vacancy.
  • Click all links in this vacancy announcement to view additional information or instructions.
  • You MUST select at least ONE ELIGIBILITY to be considered for this position.
  • All documents submitted for this announcement must be legible to make qualification or eligibility determinations.
  • A probationary period may be required.
NIST strives to build a flexible and encouraging work environment to bring out the best in our employees. To help our employees balance responsibilities at home and at work, NIST offers a variety of work-life flexibilities. For more information, please visit our Careers website.

Candidates should be committed to improving the efficiency of the Federal government, passionate about the ideals of our American republic, and committed to upholding the rule of law and the United States Constitution.

How you will be evaluated

You will be evaluated for this job based on how well you meet the qualifications above.

Please prepare a resume that is no longer than two pages; only the first two pages will be considered during the review process. Ensure your font is 11 points or larger and upload your resume as a .pdf document. This helps ensure your formatting looks exactly the way you intended.

How you will be evaluated: You will be evaluated for this job based on how well you meet the qualifications above.

You will be assessed on the following competencies (knowledge, skills, abilities, and other characteristics): Administration and Management, Chemistry, Oral Communication, and Research

Once the announcement has closed, a review of your resume and supporting documentation will be used to determine whether you meet the qualification requirements listed in this announcement. Overstating your qualifications and/or experience in your application materials or application questionnaire may result in your removal from consideration.

Subject Matter Experts (SMEs) may be used to review your resume to determine your technical qualifications for this position based on the required specialized experience. SMEs will review ONLY two (2) pages of your resume. SMEs will not review additional information beyond your resume.

Referral: All applicants may be referred to the selecting official for consideration. Under Direct Hire Authority, applicants are not rated and ranked, and veteran preference does not apply.

CTAP or ICTAP eligibility: If you are a displaced or surplus Federal employee eligible for the Career Transition Assistance Plan (CTAP) or Interagency Career Transition Assistance Plan (ICTAP), you must be determined eligible and rated as well-qualified to receive special selection priority. "Well Qualified" means that in addition to meeting the minimum qualification requirements and selective placement factor(s), if applicable, you must receive a score of 85 or higher. Please review the following site regarding required documents to support CTAP or ICTAP eligibility and additional information regarding this authority - Section 8: Hiring Paths at NIST | NIST

National Institute of Standards and Technology

NIST works with industry and science to advance innovation and improve quality of life.

Agency contact information

Erin Fannin
Email
erin.fannin@nist.gov
Address
Chemical Sciences Division
100 Bureau Drive
Gaithersburg, MD 20899
US

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https://www.nist.gov/careers

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